| 1400 – 1499 | - Al-Andalus (Muslim Iberia)安达卢斯(穆斯林统治时期)711 – 1492
- Reconquista收复失地运动718 – 1492
- Catholic Monarchs天主教双王(卡斯蒂利亚与阿拉贡联合)1469 – 1516
- Spanish Inquisition西班牙宗教裁判所1478 – 1834
- Spanish Empire西班牙帝国1492 – 1898
- Fall of Granada格拉纳达陷落1492
- Columbus reaches the Americas哥伦布抵达美洲1492
| - Da Gama's sea route to India达·伽马开辟通往印度的航路1498
| - First Nations and Inuit peoples原住民(第一民族与因纽特人)10000 BCE – 1534 · Canada
- Pre-Columbian peoples (Diaguita, Guaraní, Tehuelche)前哥伦布时期民族(迪亚吉塔、瓜拉尼、特维尔切)1000 BCE – 1535 · Argentina
- Indigenous peoples (Caribs, Arawaks, Timoto-Cuica)原住民族(加勒比人、阿拉瓦克人、蒂莫托-库伊卡人)1000 BCE – 1497 · Venezuela
- Pre-Columbian cultures (Muisca, San Agustín)前哥伦布时期文化(穆伊斯卡、圣阿古斯丁)100 BCE – 1537 · Colombia
- Mapuche and pre-Columbian peoples马普切人与前哥伦布时期民族500 – 1540 · Chile
- Maya Postclassic period玛雅后古典期900 – 1524 · Mexico
- Aztec Empire阿兹特克帝国1325 – 1521 · Mexico
- Inca Empire印加帝国1438 – 1533 · Peru
- Columbus lands in Cuba哥伦布登陆古巴1492 · Cuba
- European exploration (Cabot, Cartier)欧洲人的探索(卡伯特、卡蒂埃)1497 – 1543 · Canada
- Columbus reaches the Venezuelan coast哥伦布抵达委内瑞拉海岸1498 · Venezuela
- Spanish conquest and Bogotá founded西班牙征服与波哥大建城1499 – 1538 · Colombia
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| 1500 – 1599 | - Spanish Golden Age黄金世纪1500 – 1681
- Habsburg Spain哈布斯堡西班牙1516 – 1700
- Spanish Armada defeated无敌舰队覆灭1588
| - Height of the Portuguese Empire葡萄牙帝国的鼎盛1500 – 1580
- Cabral reaches Brazil卡布拉尔抵达巴西1500
- Iberian Union伊比利亚联盟1580 – 1640
| - Portuguese arrival葡萄牙人抵达1500 · Brazil
- Spanish rule西班牙统治1511 – 1898 · Cuba
- Balboa sights the Pacific巴尔沃亚望见太平洋1513 · Panama
- Spanish colonization and Caracas founded西班牙殖民与加拉加斯建城1515 – 1777 · Venezuela
- Panama City founded巴拿马城建立1519 · Panama
- Spanish conquest and rule西班牙征服与统治1521 – 1821 · Mexico
- Spanish conquest; Granada and León founded西班牙征服;格拉纳达与莱昂建城1524 · Nicaragua
- Spanish conquest of Cuzcatlán西班牙征服库斯卡特兰1524 – 1539 · El Salvador
- Spanish conquest西班牙征服1524 – 1697 · Guatemala
- Spanish conquest and Lempira's resistance西班牙征服与伦皮拉的抵抗1524 – 1539 · Honduras
- Colonial Brazil (sugar and gold)殖民地巴西(蔗糖与黄金)1530 – 1808 · Brazil
- Spanish conquest (Pizarro)西班牙征服(皮萨罗)1532 – 1533 · Peru
- Spanish colonization and Buenos Aires西班牙殖民与布宜诺斯艾利斯建城1536 – 1776 · Argentina
- Arauco War (Mapuche resistance)阿劳科战争(马普切人的抵抗)1536 – 1656 · Chile
- Spanish conquest and Santiago founded西班牙征服与圣地亚哥建城1540 – 1541 · Chile
- Viceroyalty of Peru秘鲁总督辖区1542 – 1824 · Peru
- Spanish Florida (St. Augustine)西属佛罗里达(圣奥古斯丁)1565 · US
- Roanoke colony罗阿诺克殖民地1585 – 1590 · US
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| 1600 – 1699 | | - Restoration of independence王政复辟(恢复独立)1640
| - Colonial period殖民时期1607 – 1765 · US
- Jamestown, Virginia founded by the English英国人建立弗吉尼亚詹姆斯敦1607 · US
- New France新法兰西1608 – 1763 · Canada
- Captaincy General of Guatemala危地马拉都督府1609 – 1821 · Central America
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| 1700 – 1799 | - War of the Spanish Succession西班牙王位继承战争1701 – 1714
| - 1755 Lisbon earthquake1755年里斯本大地震1755
| - Viceroyalty of New Granada新格拉纳达总督辖区1717 – 1810 · Colombia
- Cacao economy and the Guipuzcoana Company可可经济与吉普斯夸公司1728 – 1785 · Venezuela
- British conquest (Seven Years' War)英国征服(七年战争)1754 – 1763 · Canada
- British capture of Havana英国占领哈瓦那1762 – 1763 · Cuba
- American Revolution and Confederation period美国革命与邦联时期1765 – 1783 · US
- Viceroyalty of the Río de la Plata拉普拉塔总督辖区1776 – 1810 · Argentina
- Captaincy General of Venezuela委内瑞拉都督辖区1777 – 1811 · Venezuela
- Revolt of the Comuneros公社起义1781 · Colombia
- Simón Bolívar西蒙·玻利瓦尔1783 – 1830 · Venezuela
- Sugar boom and slavery蔗糖繁荣与奴隶制1791 – 1886 · Cuba
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| 1800 – 1899 | - Peninsular War半岛战争1808 – 1814
- Spanish American wars of independence西属美洲独立战争1808 – 1833
| - Napoleonic invasions拿破仑入侵1807 – 1814
| - Independence era独立时期1808 – 1829 · Mexico
- Portuguese court moves to Rio葡萄牙宫廷迁至里约1808 – 1821 · Brazil
- May Revolution and independence五月革命与独立1810 – 1816 · Argentina
- Independence独立1810 – 1818 · Chile
- Independence and Gran Colombia独立与大哥伦比亚1810 – 1819 · Colombia
- War of independence独立战争1810 – 1823 · Venezuela
- Declaration of Independence独立宣言1811 · Venezuela
- First Cry of Independence第一次独立呼声1811 · El Salvador
- War of 18121812年战争1812 – 1815 · Canada
- Battle of Boyacá博亚卡战役1819 · Colombia
- Part of Gran Colombia大哥伦比亚时期1819 – 1830 · Venezuela
- Civil wars and national unification内战与国家统一1820 – 1861 · Argentina
- First Mexican Empire墨西哥第一帝国1821 – 1823 · Mexico
- Independence独立1821 – 1824 · Peru
- Central American independence中美洲独立1821 · Central America
- Part of Colombia属于哥伦比亚1821 – 1903 · Panama
- Independence — Empire of Brazil独立——巴西帝国1822 · Brazil
- Federal Republic of Central America中美洲联邦共和国1823 – 1841 · Central America
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